Anti-Human IgM Antibody |
R1511-23 |
HUABIO |
100ul |
EUR 189 |
|
Description: Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens. The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen. IgM antibodies play an important role in primary defense mechanisms. They have been shown to be involved in early recognition of external invaders like bacteria and viruses, cellular waste and modified self, as well as in recognition and elimination of precancerous and cancerous lesions. The membrane-bound form is found in the majority of normal B-cells alongside with IgD. Membrane-bound IgM induces the phosphorylation of CD79A and CD79B by the Src family of protein tyrosine kinases. It may cause death of cells by apoptosis. It is also found in soluble form, which represents about 30% of the total serum immunoglobulins where it is found almost exclusively as a homopentamer. After the antigen binds to the B-cell receptor, the secreted form is secreted in large amounts. |
Goat Antibody Laboratories manufactures the goat anti-human igm antibody reagents distributed by Genprice. The Goat Anti-Human Igm Antibody reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. To purchase these products, for the MSDS, Data Sheet, protocol, storage conditions/temperature or for the concentration, please contact goat Antibody. Other Goat products are available in stock. Specificity: Goat Category: Anti-Human Group: Igm Antibody
Anti-human IgM antibody |
St John's Laboratory |
250 µg |
EUR 348 |
Description: These monoclonal antibodies enable sensitive and specific detection of human IgM in immunoassays such as ELISA and ELISpot. |
Anti-human IgM antibody |
St John's Laboratory |
250 µg |
EUR 391.2 |
Description: This monoclonal antibody enables sensitive and specific detection of human IgM in immunoassays such as ELISA and ELISpot. |
Anti-human IgM antibody |
St John's Laboratory |
1 ml |
EUR 420 |
Description: This monoclonal antibody enables sensitive and specific detection of human IgM in immunoassays such as ELISA. |
Anti-Human IgM antibody |
St John's Laboratory |
200 µl |
EUR 236.4 |
Description: Mouse monoclonal to Human IgM. |
Anti-Human IgM Antibody |
HUABIO |
100ul |
EUR 189 |
|
Description: Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens. The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen. IgM antibodies play an important role in primary defense mechanisms. They have been shown to be involved in early recognition of external invaders like bacteria and viruses, cellular waste and modified self, as well as in recognition and elimination of precancerous and cancerous lesions. The membrane-bound form is found in the majority of normal B-cells alongside with IgD. Membrane-bound IgM induces the phosphorylation of CD79A and CD79B by the Src family of protein tyrosine kinases. It may cause death of cells by apoptosis. It is also found in soluble form, which represents about 30% of the total serum immunoglobulins where it is found almost exclusively as a homopentamer. After the antigen binds to the B-cell receptor, the secreted form is secreted in large amounts. |
Anti-human IgM Antibody |
ABM |
100 µg |
EUR 425 |
Igm Antibody information
Goat anti-Human IgM Antibody (AP) |
abx401048-1ml |
Abbexa |
1 ml |
EUR 594 |
|
Goat Anti-Human IgM (Mu) Antibody |
abx120113-100l |
Abbexa |
100 µl |
Ask for price |
Goat Anti-Human IgM (Mu) Antibody |
abx120113-20l |
Abbexa |
20 µl |
EUR 700 |
Goat Anti-Human IgM (Mu) Antibody |
abx120113-50l |
Abbexa |
50 µl |
Ask for price |
Goat Anti-Human IgM (Mu) Antibody |
abx120116-100l |
Abbexa |
100 µl |
Ask for price |
Goat Anti-Human IgM (Mu) Antibody |
abx120116-20l |
Abbexa |
20 µl |
EUR 700 |
Goat Anti-Human IgM (Mu) Antibody |
abx120116-50l |
Abbexa |
50 µl |
Ask for price |
Goat Anti-Human IgM (Mu) Antibody |
abx023530-400l |
Abbexa |
400 µl |
Ask for price |
Goat Anti-Human IgM (Mu) Antibody |
abx023530-80l |
Abbexa |
80 µl |
EUR 550 |
Goat Anti-Human IgM (Mu) Antibody |
abx023532-400l |
Abbexa |
400 µl |
Ask for price |
Goat Anti-Human IgM (Mu) Antibody |
abx023532-80l |
Abbexa |
80 µl |
EUR 375 |
Goat Anti-Human IgM (Mu) Antibody |
abx023533-400l |
Abbexa |
400 µl |
Ask for price |
Goat Anti-Human IgM (Mu) Antibody |
abx023533-80l |
Abbexa |
80 µl |
EUR 362.5 |
Goat Anti-Human IgM Antibody (PE) |
abx401051-100g |
Abbexa |
100 µg |
EUR 462.5 |
Goat anti-Human IgM Antibody (RPE) |
abx401051-05mg |
Abbexa |
0.5 mg |
EUR 678 |
|
Goat anti-Human IgM Antibody (HRP) |
abx401509-1ml |
Abbexa |
1 ml |
EUR 526.8 |
|
Goat Anti-Human IgM Antibody (ALP) |
abx401048-100g |
Abbexa |
100 µg |
EUR 387.5 |