Goat Anti-Human Igm Antibody

Anti-Human IgM Antibody

R1511-23 100ul
EUR 189
Description: Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens. The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen. IgM antibodies play an important role in primary defense mechanisms. They have been shown to be involved in early recognition of external invaders like bacteria and viruses, cellular waste and modified self, as well as in recognition and elimination of precancerous and cancerous lesions. The membrane-bound form is found in the majority of normal B-cells alongside with IgD. Membrane-bound IgM induces the phosphorylation of CD79A and CD79B by the Src family of protein tyrosine kinases. It may cause death of cells by apoptosis. It is also found in soluble form, which represents about 30% of the total serum immunoglobulins where it is found almost exclusively as a homopentamer. After the antigen binds to the B-cell receptor, the secreted form is secreted in large amounts.

Goat Antibody Laboratories manufactures the goat anti-human igm antibody reagents distributed by Genprice. The Goat Anti-Human Igm Antibody reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. To purchase these products, for the MSDS, Data Sheet, protocol, storage conditions/temperature or for the concentration, please contact goat Antibody. Other Goat products are available in stock. Specificity: Goat Category: Anti-Human Group: Igm Antibody

Anti-Human IgM antibody

1 mg
EUR 256.8

Anti-human IgM antibody

250 µg
EUR 348
Description: These monoclonal antibodies enable sensitive and specific detection of human IgM in immunoassays such as ELISA and ELISpot.

Anti-human IgM antibody

250 µg
EUR 391.2
Description: This monoclonal antibody enables sensitive and specific detection of human IgM in immunoassays such as ELISA and ELISpot.

Anti-human IgM antibody

1 ml
EUR 420
Description: This monoclonal antibody enables sensitive and specific detection of human IgM in immunoassays such as ELISA.

Anti-Human IgM antibody

200 µl
EUR 236.4
Description: Mouse monoclonal to Human IgM.

Anti-Human IgM Antibody

100ul
EUR 189
Description: Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens. The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen. IgM antibodies play an important role in primary defense mechanisms. They have been shown to be involved in early recognition of external invaders like bacteria and viruses, cellular waste and modified self, as well as in recognition and elimination of precancerous and cancerous lesions. The membrane-bound form is found in the majority of normal B-cells alongside with IgD. Membrane-bound IgM induces the phosphorylation of CD79A and CD79B by the Src family of protein tyrosine kinases. It may cause death of cells by apoptosis. It is also found in soluble form, which represents about 30% of the total serum immunoglobulins where it is found almost exclusively as a homopentamer. After the antigen binds to the B-cell receptor, the secreted form is secreted in large amounts.

Anti-human IgM Antibody

100 µg
EUR 425

Igm Antibody information

Goat anti-Human IgM Antibody (AP)

abx401048-1ml 1 ml
EUR 594

Goat Anti-Human IgM (Mu) Antibody

abx120113-100l 100 µl Ask for price

Goat Anti-Human IgM (Mu) Antibody

abx120113-20l 20 µl
EUR 700

Goat Anti-Human IgM (Mu) Antibody

abx120113-50l 50 µl Ask for price

Goat Anti-Human IgM (Mu) Antibody

abx120116-100l 100 µl Ask for price

Goat Anti-Human IgM (Mu) Antibody

abx120116-20l 20 µl
EUR 700

Goat Anti-Human IgM (Mu) Antibody

abx120116-50l 50 µl Ask for price

Goat Anti-Human IgM (Mu) Antibody

abx023530-400l 400 µl Ask for price

Goat Anti-Human IgM (Mu) Antibody

abx023530-80l 80 µl
EUR 550

Goat Anti-Human IgM (Mu) Antibody

abx023532-400l 400 µl Ask for price

Goat Anti-Human IgM (Mu) Antibody

abx023532-80l 80 µl
EUR 375

Goat Anti-Human IgM (Mu) Antibody

abx023533-400l 400 µl Ask for price

Goat Anti-Human IgM (Mu) Antibody

abx023533-80l 80 µl
EUR 362.5

Goat Anti-Human IgM Antibody (PE)

abx401051-100g 100 µg
EUR 462.5

Goat anti-Human IgM Antibody (RPE)

abx401051-05mg 0.5 mg
EUR 678

Goat anti-Human IgM Antibody (HRP)

abx401509-1ml 1 ml
EUR 526.8

Goat Anti-Human IgM Antibody (ALP)

abx401048-100g 100 µg
EUR 387.5